바이오이미징

바이오이미징

혁신적인 체내 다층 조직 이미징화

  • 폭 넓은 가변 파장범위와 단 펄스 ultrafast레이저로 심층 체내 이미징 구현
  • 이미징 분야에서 입증된 레이저
  • 다년간의 운영을 통한 최고의 신뢰성

바이오이미징

Spectra-Physics사는 바이오 이미징에 사용되는 레이저 시장의 선두주자로, 우수한 심도를 자랑하는 획기적인 성능의 InSight X3 ultrafast 레이저를 개발해 다광자 이미징에 또 다른 혁신을 가져왔습니다. 바이오 이미징 응용분야에서 수 천대의 레이저 판매를 기록함으로써, 신뢰성 높은 솔루션을 보장합니다.

자사의 전문가와 함께 레이저 응용분야에 대한 귀사의 니즈와 과제에 대해 논의하여 해결방안을 모색하시길 바랍니다.

 

Insight DeepSee ultrafast laser

InSight X3

Widely tunable ultrafast laser system for multiphoton images

new

생물이미징 응용분야

Mouse brain, hippocampus region; imaged with femtoTrain™.
Courtesy of Sabine Scheibe, LMU Munich and Tilman Franke, FEI Munich GmbH



Mouse barrel cortex, after clearing.
Courtesy of Gabriel Jones, Steven Petrou, University of Melbourne, Australia



Hippocampus CA3 pyramidal neuron; imaged with InSight® DS+™.
Courtesy of Karina Alvina, Albert Einstein College of Medicine



Multicolor image of live mouse brain; imaged with InSight DS+.
Courtesy of Naoki Honkura and Takeshi Imamura, Ehime University Graduate School of Medicine



Zebrafish embryo brain development, CFP, YFP, mCherry imaged at 860 nm and 1041 nm with InSight® DS+™.
Courtesy of Dr. Nadine Peyrieras, CNRS, Gif sur Yvette, France and LaVision Biotec



Maximum intensity projection of zebrafish embryo development, taken from both sides over 8 hours; imaged with InSight DS+.
Courtesy of Dr. Nadine Peyrieras, CNRS, Gif sur Yvette, France and LaVision Biotec



Z-stack of transgenic zebrafish larvae, labeled with GFP and CFP; imaged with Mai Tai® DeepSee™.
Courtesy of Dr. Rachel Wong, University of Washington, Seattle



Transgenic zebrafish embryo retina, revealing various neuronal cell types, imaged at 927 nm and 1041 nm with InSight DS+.
Courtesy of Dr. Xana Almeida, University of Cambridge, UK



Lymph vessel; imaged with InSight® DS+™.
Courtesy of Dr. Cameron Newell, Monash, University, Melbourne, Australia



Continuous tracking of T cells (tagged with CMPTX, imaged at 1080 nm) and dendritic cells
(tagged with GFP, imaged at 925 nm) interacting in mouse skin over several hours; imaged with InSight DS+.
Courtesy of Dr. Michael Kuligowski, Centenary Institute of Cancer Research and Cell Biology, Sydney, Australia



Continuous tracking of T cells (tagged with CMPTX, imaged at 1080 nm) and dendritic cells
(tagged with GFP, imaged at 925 nm) interacting in mouse skin over several hours; imaged with InSight DS+.
Courtesy of Dr. Michael Kuligowski, Centenary Institute of Cancer Research and Cell Biology, Sydney, Australia



Mouse ear, showing collagen (blue) and GFP labelled T cells (green); imaged with Mai Tai® DeepSee™.
Courtesy of Dr. Claudio Vinegoni, Mass General Hospital, Harvard University



Retinal ganglion cell; imaged with Mai Tai.
Courtesy of Dr. Gregory Schwartz, Northwestern University



Chemically cleared mouse heart total depth of 3.5 mm; imaged with Mai Tai DeepSee.
Courtesy of Mayandi Sivaguru, University of Illinois Urbana Champaign and Sakthivel Sadayappan, Loyola University, Chicago



Human meibomian gland, CARS imaging the lipid rich meibocytes and SHG visualizing the surrounding collagen;
acquired with InSight® DS+™.
Courtesy of Dr. Eric Potma, UC Irvine



SRS image of fatty liver, pump 802 nm and Stokes at 1040 nm; acquired with InSight DS+.
Courtesy of Dr. Ji-XIn Cheng, Purdue University



SRS image of spinal cord, pump 802 nm and Stokes at 1040 nm; acquired with InSight DS+.
Courtesy of Dr. Ji-XIn Cheng, Purdue University



CARS Z-stack of C.Elegans worm, visualizing lipids 19.
Courtesy of Dr. Daewon Moon and Dr. Hyunmin Kim, DGIST Daegu Gyeongbuk Institute of Science and Technology (DGIST)



CARS and MPEF imaging of C. Elegans, neuron cells labelled with GFP, lipid droplets revealed with CARS.
Courtesy of Dr. Daewon Moon and Dr. Hyunmin Kim, DGIST Daegu Gyeongbuk Institute of Science and Technology (DGIST)



Zebrafish embryo (6 hours post fertilization) using label free THG at 1140 nm; imaged with InSight® DS+™.
Courtesy of Dr. Nadine Peyrieras, CNRS, Gif sur Yvette, France



Mouse blood vessel wall, SHG and multiphoton excited fluorescence imaging with HighQ-2™.
Courtesy of Dr. Marc van Zandvoort, Maastrich University



Mouse mammary gland, label free image of collagen (SHG, magenta) and adipocytes (THG, yellow), imaged with InSight DS+™.
Courtesy of Dr. Marie Irondelle, Institut Curie/CNRS, Paris, France



3D images from a mouse brain cerebellum extending 1 mm deep into the tissue acquired via 3PF (left)
and THG (right) microscopy at 1.3 μm using a Spirit laser with a Spirit-NOPA.
Courtesy of Chris Xu, with permission from SPIE Publications: Wang, et. al., “In vivo three-photon
imaging of deep cerebellum,” Proc. SPIE:  Multiphoton Microscopy in the Biomedical Sciences
XVIII, vol. 10498, 2018.

Mouse kidney, with CARS (red), SHG (blue) and autofluorescence (green); imaged with Mai Tai® HP plus Inspire™ OPO.
Courtesy of Dr. Eric Potma, UC Irvine, CA



C. elegans, with CARS mapping out lipid rich areas and two-photon excited fluorescence from GFP and dsRed;
imaged with InSight® DS+™.
Courtesy of Dr. Eric Potma, UC Irvine, CA

바이오 이미징을 위한 레이저

제품유형파장펄스폭
new
InSight X3
멀티포톤 이미징용 파장가변형 Ultrafast 레이저 시스템
Ultrafast 680–1300 nm <120 fs  
Mai Tai DeepSee
폭넓은 가변범위와 최고출력을 위한 분산 보상 장치가 내장
690–1040 nm 70–100 fs  
Mai Tai
폭넓은 가변범위와 극초단 펄스 폭
690–1040 nm 70–100 fs  
new
Spirit
초정밀 미세가공의 새로운 표준을 제시해 드립니다
515, 520, 1030, 1040 nm 400 fs  
HighQ-2
초소형 턴키 방식의 단일 파장의 펨토초 레이저
Fixed, 1045 nm <250 fs  
femtoTrain
소형의 턴키 방식의 높은 에너지 펨토초 레이저
Fixed, 1040 nm <220 fs  
Inspire
UV(자외선)에서 IR(적외선) 까지 커버하는 초광대역 스펙트럼 적용범위의 광 파라메트릭 진동기
345–2500 nm 80–250 fs  
Excelsior One
초소형 올인원 CW 레이저 (OEM)
CW 375, 405, 445, 473, 488, 532, 542, 561,
642, 785, and 1064 nm
N/A  
Excelsior
초소형 CW레이저 (연구개발 및 OEM)
375, 405, 440, 473, 488, 505, 515, 532, 542, 561,
594, 642, 785, and 1064 nm
 

응용분야안내

이광자 여기 형광 현미경
CARS 이미징을 통한 기타 다중 이미징 기술 강화
가변 레이저에 탑재되는 컴퓨터 제어식 가변 감쇠기
레이저에 탑재되는 가변 감쇠기

기술자료

자원 라이브러리